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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN3
All Species:
18.18
Human Site:
S268
Identified Species:
28.57
UniProt:
Q6P5Z2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P5Z2
NP_037487.2
889
99421
S268
V
P
G
Y
P
Q
P
S
G
T
P
V
K
P
T
Chimpanzee
Pan troglodytes
XP_001159776
886
99121
S268
V
P
G
Y
P
Q
P
S
G
T
P
V
K
P
T
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
S381
V
P
G
Y
P
Q
P
S
G
T
P
V
K
P
T
Dog
Lupus familis
XP_548434
951
104664
S330
V
S
G
N
P
Q
P
S
G
V
L
V
K
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8K045
878
97863
L261
M
L
G
N
P
Q
P
L
G
T
L
V
K
P
I
Rat
Rattus norvegicus
O08874
985
112050
Y319
M
L
S
T
Q
N
Q
Y
S
T
L
S
K
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
P368
T
L
G
S
L
C
S
P
S
A
L
G
K
P
T
Chicken
Gallus gallus
XP_422357
1013
114806
Y344
V
I
S
T
Q
N
Q
Y
S
T
L
S
K
P
A
Frog
Xenopus laevis
Q7ZX15
486
56292
Zebra Danio
Brachydanio rerio
XP_697542
940
106140
S307
L
R
S
S
S
S
A
S
S
S
L
F
K
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
M124
V
V
S
K
C
P
G
M
R
D
E
Q
P
A
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
P181
M
A
L
F
L
R
Q
P
T
F
C
A
H
C
K
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
S179
I
P
Y
R
A
R
N
S
I
T
S
L
N
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
R256
T
K
P
S
R
N
D
R
W
S
E
D
F
Q
I
Red Bread Mold
Neurospora crassa
P87253
1142
127954
R342
D
I
V
E
E
L
R
R
K
K
I
E
A
E
M
Conservation
Percent
Protein Identity:
100
97.7
81.5
84.2
N.A.
83.2
49.9
N.A.
64.2
48.9
26.2
52.2
N.A.
28
N.A.
29.1
41.5
Protein Similarity:
100
97.8
82.9
87.6
N.A.
88.4
63.6
N.A.
72.9
63
36.6
67.6
N.A.
41.5
N.A.
43.9
58.2
P-Site Identity:
100
100
100
73.3
N.A.
60
20
N.A.
26.6
26.6
0
20
N.A.
6.6
N.A.
0
20
P-Site Similarity:
100
100
100
73.3
N.A.
66.6
26.6
N.A.
26.6
26.6
0
33.3
N.A.
6.6
N.A.
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
27.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
43.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
7
0
7
0
0
7
0
7
7
7
20
% A
% Cys:
0
0
0
0
7
7
0
0
0
0
7
0
0
7
0
% C
% Asp:
7
0
0
0
0
0
7
0
0
7
0
7
0
0
0
% D
% Glu:
0
0
0
7
7
0
0
0
0
0
14
7
0
7
0
% E
% Phe:
0
0
0
7
0
0
0
0
0
7
0
7
7
0
0
% F
% Gly:
0
0
40
0
0
0
7
0
34
0
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
7
14
0
0
0
0
0
0
7
0
7
0
0
0
14
% I
% Lys:
0
7
0
7
0
0
0
0
7
7
0
0
60
0
14
% K
% Leu:
7
20
7
0
14
7
0
7
0
0
40
7
0
0
0
% L
% Met:
20
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
14
0
20
7
0
0
0
0
0
7
0
0
% N
% Pro:
0
27
7
0
34
7
34
14
0
0
20
0
7
60
7
% P
% Gln:
0
0
0
0
14
34
20
0
0
0
0
7
0
7
0
% Q
% Arg:
0
7
0
7
7
14
7
14
7
0
0
0
0
0
0
% R
% Ser:
0
7
27
20
7
7
7
40
27
14
7
14
0
7
0
% S
% Thr:
14
0
0
14
0
0
0
0
7
47
0
0
0
0
34
% T
% Val:
40
7
7
0
0
0
0
0
0
7
0
34
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
0
0
7
20
0
0
0
14
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _